Saturday, 18 July 2015
21 October 2020

«poison or youth elixir»

2010 October 29

Dr. Avideh Motmaen-Far, Osteopath D.O. /Radio Koocheh

avideh@avideh.net

Unfortunately for all of us, it is true that we get older. Some of us try Botox injections — which prevent wrinkles by partially paralyzing facial muscles but how much we really know about it? What are its indications, side effects and interactions? Today, I am trying to bring you some facts. Botulinum toxin is a protein produced by the bacteria Clostridium Botulinum. In 1897, ”Emile van Ermengem” identified this bacteria although it took 2 scientists ”Snipe” and ”Sommer” a few years to purify the toxin and finally only in 1949 Burgen’s group discovered that botulinum toxin blocks neuromuscular transmission. In the late 1960s Alan Scott, M.D., a San Francisco based Ophthalmologist and Edward Schantz were the first to work on botulinum toxin for therapeutic purposes. In 1980, BTX-A was officially used for the first time in humans to treat strabismus, and blepharospasm (uncontrollable blinking). In 1993, ”Bushara” and ”Park” used botulinum toxin injections to inhibit sweating, which was the first demonstration use of BTX-A on autonomic nervous system.

Allergic reactions to BOTOX or BOTOX Cosmetic may include: itching, rash, red itchy welts, wheezing, asthma symptoms, dizziness or feeling faint

Since early 80’s this favourite drug of our time was only used for the treatments of Strabismus and blepharospasm. The patients had to receive an injection every 4 to 6 months. In 1989, ”Dr. Richard Clark”, a plastic surgeon from Sacramento, California originally documented the cosmetic effect of BTX-A on wrinkles in the journal Plastic and Reconstructive Surgery. In 1992, Canadian husband and wife ophthalmologist and dermatologist physicians ”Carruthers JD” and ”Carruthers JA” were the first to publish a study on BTX-A for the treatment of glabellar frown lines. Finally on April 12, 2002, the FDA announced regulatory approval of botulinum toxin type A (Botox Cosmetic) to temporarily improve the appearance of moderate-to-severe frown lines between the eyebrows (glabellar lines). Since then, cosmetic use of botulinum toxin type A has become widespread because many celebrities view it as less intrusive solution than plastic surgery.

BOTOX is a prescription medicine that is injected into muscles and used to treat increased muscle stiffness in elbow, wrist, and finger muscles in adults with upper limb spasticity. It is also indicated to to treat the abnormal head position and neck pain that happens with cervical dystonia (CD) in adults, certain types of eye muscle problems (strabismus) or abnormal spasm of the eyelids (blepharospasm) in people 12 years and older. BOTOX is also injected into the skin to treat the symptoms of severe underarm sweating (severe primary axillary hyperhydrosis) when medicines used on the skin (topical) do not work well enough.

BOTOX Cosmetic is a prescription medicine that is injected into muscles and used to improve the look of moderate to severe frown lines between the eyebrows (glabellar lines) in adults younger than 65 years of age for a short period of time (temporary).

BOTOX Cosmetic is not recommended for use in children younger than 18 years of age. It is not known whether BOTOX and BOTOX Cosmetic are safe or effective for other types of muscle spasms or for severe sweating anywhere other than the armpits. Nonetheless, there are important information you should know about BOTOX and BOTOX Cosmetic.

BOTOX and BOTOX Cosmetic may cause serious side effects that can be life threatening. Problem such as swallowing, speaking, or breathing can happen hours to weeks after an injection of BOTOX or BOTOX Cosmetic usually because the muscles that you use to breathe and swallow can become weak after the injection.  People with certain breathing problems may need to use muscles in their neck to help them breathe. These patients may be at greater risk for serious breathing problems with BOTOX or BOTOX Cosmetic. Death can happen as a complication if you have severe problems with swallowing or breathing after treatment with BOTOX or BOTOX Cosmetic. Seek emergency help if this is the case.  Other side effects of BOTOX® Cosmetic include dry mouth, discomfort or pain at the injection site, tiredness, headache, neck pain, and eye problems: double vision, blurred vision, decreased eyesight, drooping eyelids, swelling of your eyelids, and dry eyes.

Spread of toxin effects may affect areas of the body away from the injection site and cause symptoms of a serious condition called botulism. The symptoms of botulism include loss of strength and muscle weakness all over the body, double vision, blurred vision and droping eyelids, hoarseness or change or loss of voice (dysphonia), trouble saying words clearly (dysarthria) and loss of bladder control. These symptoms can happen hours to weeks after you receive an injection of BOTOX or BOTOX Cosmetic.

BOTOX Cosmetic is a prescription medicine that is injected into muscles and used to improve the look of moderate to severe frown lines between the eyebrows (glabellar lines) in adults younger than 65 years of age for a short period of time (temporary). BOTOX Cosmetic is not recommended for use in children younger than 18 years of age.

Allergic reactions to BOTOX or BOTOX Cosmetic may include: itching, rash, red itchy welts, wheezing, asthma symptoms, dizziness or feeling faint. Tell your doctor or get medical help right away if you are wheezing or have asthma symptoms, or if you become dizzy or faint.

Use of Botox is not indicated in case of a neuromuscular disorder such as Amyotrophic Lateral Sclerosis (ALS), Myasthenia Gravis, and Lambert-Eaton syndrome . It is not yet known whether it will be harmful to an unborn baby or whether botulinum toxin type A passes into breast milk. Do not use botulinum toxin type A without first talking to your doctor if you are breast-feeding a baby.

If you plan to have Botox injections, make sure your Doctor knows if you have recently received an antibiotic by injection, take muscle relaxants, take an allergy or cold medicine, take a sleep medicine or have received any other botulinum toxin product in the last four months.

Anyways, I personally think that I will try to age gracefully. Years can wrinkle our skin but to give up enthusiasm wrinkle our soul.

«نوشته فوق می تواند نظر نویسنده باشد و الزامن نظر رادیو کوچه نیست»

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