Saturday, 18 July 2015
29 November 2020
Koocheh Salamati – hair loss

«wastes women’s beauty and men’s youth»

2010 November 19

Dr. Avideh Motmaen-Far Osteopath D.O. /Radio Koocheh

avideh@avideh.net

Society usually accepts a bald man, but it’s not an acceptable thing for a woman. So much emphasis and value is placed on a woman’s head of hair; we can not even start to compare the impact on men versus women. People tend not to associate pattern baldness with women, but it is just as common in women, though the timing and pattern of hair loss is different. 25% of 30 million women in the United States will experience hereditary hair thinning and hair loss affects.

Hair is important for temperature regulation, physical protection, sensory activity, and social interactions. Hair is formed in hair follicles, which are complex mini-organs in the skin specialized for this purpose. All hair follicles are formed during fetal development, then new hair is generated in the hair follicle by continually undergoing phases of recession, rest, and growth throughout life. The length of the hair is determined by the duration of the growth phase; for example, the growth phase for scalp hair is 2 to 3 years while the growth phase for eyebrows last a few months. Hair grows more or less 1 centimeter per month. When a hair falls out, it is replaced within 6 months by a new hair. After the growth phase, hair formation ceases, and the follicle recedes and enters a period of rest. After a period of rest, aproximately 3 to 4 months later, a new growth period starts, and the old hair is ejected and lost from the body. About 90 percent of the hair on your scalp is growing at any one time and about 10 percent of the hair on your scalp, at any one time, is in a resting phase. The reason for this complex regulation of hair growth is not understood, but it has been suggested that it makes it possible to adjust hair growth to the season.

Androgens also have other important functions in both males and females, such as regulating hair growth and sex drive.

Although due to the normal hair growth cycle, it is normal to shed some hair each day, but some people may experience excessive hair loss. Hair loss can affect men, women and children. A number of things can cause excessive hair loss. ”Traction Alopecia” is most commenly found in people who pull on their hair excessively to do ponytails or cornrows. ”Trichotillomania” is caused by compulsive pulling and bending of the hair. Traumas such as chemotherpy, major surgery, poisoning, and severe stress may cause a hair loss condition known as ”Telogen Effluvium”. Iron deficiency, radiotherapy to the head for the treatment of certains cancers, myotic infections can also cause massive hair loss. Alopecia Areata is an autoimmune disorder can result is hair loss ranging from one spot baldness to the entire body. Hypothyroidism cause frontal hair loss associated with the thinning of the outer third ogf the eyebrows while hyperthyroidism cause parietal hair loss. Localized or diffuse hair loss may also occur in ”cicatricial alopecia” in cases such as Lupus Erythematosus. Tumors and skin outgrowths also induce baldness. ”Congenital triangular alopecia” is a condition in which triangular or oval shaped patch of hair loss in temple area of the sculp occurs mostly in younge children. The affected area does not contain any hair follicles.

Many women can experience hair loss about 3 months after giving birth. This kind of hair loss is due to decreased levels of Oestrogen after the pregnancy. Some medicines such as Anticoagulants, medicines used for gout, high blood pressure or heart problems, vitamin A in high doses, birth control pills and antidepressants can cause hair loss. Hot oil hair treatments or chemicals used in permanents (also called “perms”) may cause inflammation of the hair follicle, which can result in scarring and and permanent hair loss.

”Androgenetic Alopecia” or male-pattern baldness or permanent-pattern baldness is the most common cause of hair loss in men. Researchers have determined that this form of hair loss is related to hormones called androgens, particularly an androgen called dihydrotestosterone (DHT). Androgens are important for normal male sexual development before birth and during puberty. Androgens also have other important functions in both males and females, such as regulating hair growth and sex drive.   ”Androgenetic Alopecia” is also the most common form of hair loss in women which usually has a strong genetic component that can be inherited from either the mother or father. This type of hair loss can start as early as the late teens — and the earlier it starts, the more severe the hair loss tends to be. While pattern hair loss affects both men and women, it is very different in women.  Female-pattern hair loss is not characterized by a receding hairline or bald spot on top of the scalp as is common in men. In women, the frontal hairline is usually maintained, but there is visible thinning over the crown. In addition, in both men and women, hairs are miniaturized due to a shortened growth cycle.

In addition, in both men and women, hairs are miniaturized due to a shortened growth cycle.

Baldness is not only a human trait. Some other primates such as chimpanzee, stump-tailed macaques and south American uakari show progressive thinning of the hair on the scalp after adolescence. Adult stump-tailed macaques, in fact, are commonly used in laboratories for the testing of hair-regrowth treatments.

Leif Carlsson’s research team at Umeå University in Sweden has shown that the activation of the gene Lhx2 leads to increased hair growth. The scientists have been able to show that Lhx2 is functionally involved in the formation of hair, as hair follicles in which Lhx2 has been inactivated cannot produce hair. The Lhx2 gene is active during the hair follicle’s growth phase and is turned off during the resting period. Moreover, transgenic expression of Lhx2 after birth is sufficient to activate the growth phase and stimulate hair growth. Leif Carlsson and his colleagues found that Lhx2 is primarily expressed outside the so-called bulge region of the hair follicle, where the follicle’s stem cells are found. The Umeå researchers have also shown that Lhx2 is necessary for the hair follicle’s growth (anagen) phase to proceed and for the hair follicle’s structuring. Thus, Lhx2 is a gene that is important for the regulation of hair growth.

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